Overall objectives:

1 - Adquirir, consolidar e aprofundar os conhecimentos fundamentais de laboratório, com o fim compreender e realizar os procedimentos e tarefas básicas num ambiente laboratorial.
2 - Learn and apply laboratory operating and safety rules.
3 - Know and understand how to operate, use and maintain laboratory equipment and materials.
4 - Learn how to handle reagents, prepare solutions, use standards, prepare and handle samples, understanding the importance of these operations in the context of future professional and industrial activity.
5 - Understand and carry out work with solutions: know concentration units; prepare solutions; make forecast calculations; assess the need for standardization

Syllabus:

1. - Theoretical-practical component:
1.1 - Fundamentals of laboratory chemistry. Chemical elements. Behavior of chemical elements: acid, base, ionic. Mendeleev's periodic table. Classification of chemical elements and their properties. Chemical composition of biological matrices. Water, pH, ionic balances. Molecules and molecular bonds.
1.2 - Laboratory structure, organization, and safety. Laboratory work zones. Material storage. Traffic flow. Safety equipment. Reagent storage. Waste Management. Emergency preparedness. Electrical safety. Documentation.
1.3 - Laboratory equipment. Hottes. Centrifuges. Scales. Baths. Agitators. pH meters. Titrators. Pipettes. Spectrophotometers.
1.4 - Laboratory materials. Glassware. Plastics. Metals. Porcelain. Accessories and disposable materials.
1.5 - Chemical handling and safety. Adequate ventilation. Labeling, identification and careful handling.
1.6 - Experimental draw. Identification of variables. Sample selection. Random allocation. Manipulation of independent variables. Replication.
1.7 - Laboratory techniques. Weighing. Volume measurement. Titration. Distillation. Extraction. Chromatography. Filtration. Centrifugation. Precipitation and pH measurement.
1.8 - Laboratory notebooks and documentation. Measurements and data analysis. Data collection: precision and accuracy; units of measurement. Statistical analysis. Graphic representation. Data interpretation. Error propagation. Hypothesis testing. Scientific reports and articles. Software. Validation of methods. Peer review.
1.9 - Quality control and validation. Establishment of standards. Sampling control. Equipment calibration. Process control and validation reports. Problem solving.
1.10 - Ethical issues. Biosafety. Preservation of the environment. Responsible use of resources. Scientific integrity. Open access and sharing of results.
2. - Laboratory Component
2.1 - Demonstration of laboratory equipment, materials and reagents.
2.2 - Demonstration of laboratory safety equipment.
2.3 - Measuring techniques using precision and analytical balances, pipettes, beakers and thermometers.
2.4 - Preparation of solutions of different concentrations, standard solutions, acid and base solutions and compound extraction and purification solutions.
2.5 - Introduction to simple and fractional distillation techniques, filtration and separation of homogeneous and heterogeneous mixtures.
2.6 - Acid-base titrations using indicators.
2.7 - Introduction to extract production and compound purification techniques.
2.8 - Application of spectrophotometry techniques to construct calibration lines and in vitro quantification of extracts and chemical compounds.
2.9 - Preparation of laboratory notebooks and scientific reports.

Literature/Sources:

Chang, R., Goldsby, K. A. , 2013 , Química, 11.ª ed. , McGraw-Hill
Atkins, P., Laverman, L., Jones; L. , 2012 , Princípios de Química: Questionando a Vida Moderna e o Meio Ambiente, 5.ª ed. , Bookman
Bursten, B. E., Murphy, C., Stoltzfus, M. E., Brown, T.E., Lemay, H. E., Woodward, P. , 2005 , Chemistry: The Central Science, Global Edition, 13.ª ed. , Prentice-Hall
M. Simões, J. A., Castanho, M. A. R. B, I. M. S., Lampreia, M. M. P., C. A., Nieto de Castro, M. T., Pamplona, F. J. V. S. , 2017 , Guia do Laboratório de Química e Bioquímica , Lidel
Matos, A. C., Palma; C. M., Pereira, P. C. , 2009 , Técnicas de Laboratório, Química Laboratorial , Edições Universitárias Lusófonas
vários , http://www.periodicvideos.com ,
vários , https://www.tdwscience.com/videos ,
vários , https://www.acs.org/content/acs/en/education/resources/highschool/chemmatters/videos.html ,
vários , https://www.acs.org/content/acs/en/pressroom/reactions.html ,
vários , https://www.brightstorm.com/science/chemistry/ ,
Anastácio Feitosa, E.M., Barbosa, F.G.,Sampaio Forte, C.M. , 2016 , Química geral I , EdUECE

Assesssment methods and criteria:

Classification Type: Quantitativa (0-20)

Evaluation Methodology:
The aim is to acquire and apply the knowledge foreseen in the course?s objectives and syllabus contents, through an active and interdisciplinary methodology. The student must learn the basic concepts and know-how to relate them to each other, proceeding with their reinforcement, through applied learning using available tools and study visits to concrete situations of the future professional activity. To achieve the objectives and implement the syllabus, the UC's contact hours are scheduled as follows: Theoretical-practical teaching: 30 hours; Practical and laboratory teaching: 16 hours; and Field work: 10 hours. The evaluation will include several moments of evaluation applied to the theoretical-practical components, laboratory practices and field work (e.g. frequencies, works and reports), any of the elements cannot exceed a weighting of 50%. the theoretical-practical elements can be retrieved in resource.